Pharmacological Evaluation of Total Alkaloids from Nux Vomica: Effect of Reducing Strychnine Contents
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چکیده
منابع مشابه
Pharmacological evaluation of total alkaloids from nux vomica: effect of reducing strychnine contents.
The aim of the study was to investigate the possibility of improving the therapeutic efficacy of the total alkaloid fraction (TAF) extracted from processed nux vomica by reducing the strychnine contents. Most strychnine was removed from TAF to obtain the modified total alkaloid fraction (MTAF). The toxicity and pharmacokinetics of TAF and MTAF were further investigated and compared besides thei...
متن کاملTlc – Spectrophotometric Analysis of Strychnine and Brucine from the Ayurvedic Pills of Nux Vomica
Ayurvedic preparations claim on their label only the quantity of crude drugs and not the quantity of active ingredients present therein. So work was taken up to find the percentage of strychnine and brucine from Ayurvedic pills of Nux vomica powder by TLC spectrophotometric analysis, which study has not been reported earlier. However, the literature survey only revealed the following work.
متن کاملAyurvedic Processings of Nux Vomica: Qualitative and Quantitative Determination of Total Alkaloidal Contents and Relative Toxicity
The seeds of Strychnos nuxvomica Linn. (Loganiaceae) were processed as prescribed in the Ayurvedic classics. The seeds were soaked in Kanji (3 days; Sample A); boiled in cow milk (3 h; Sample B); soaked in cow urine (7 days), boiled in cow milk (3 h) and roasted in cow ghee (till swollen; Sample C) and a sample roasted in cow ghee (till swollen; Sample D). The processed nux vomica were compared...
متن کاملA rare case of strychnine poisoning by consumption of Strychnos nux- vomica leaves
Strychnine is one of the oldest poisons known to man. The source of this potent toxin is the Strychnos nux-vomica plant, which actually contains two distinct alkaloidsstrychnine and brucine. Although principally found in the seeds, these alkaloids can be isolated in varying concentrations from virtually all parts of the plant including the bark, leaves and roots[1]. Once consumed, strychnine pr...
متن کاملPoisoning by Strychinos Nux Vomica
IjOHAKNO, jih adult male, was brought to the dispensary, Aska, at 7-30 a.m., on the 17th February 1889, with the following symptoms: Giddiness of head ; a sensation of swimming of the whole body; feeling of numbness in the trunk and more markedly in the lower extremities ; dryness of throat ; slight injection of the ocular conjunctivae; heaviness of head ; occasional backward jerking of the hea...
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ژورنال
عنوان ژورنال: Molecules
سال: 2014
ISSN: 1420-3049
DOI: 10.3390/molecules19044395